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Australian TeaTree Genomes

Genomics Analysis for Two Australian Tea Trees

Species

  • Gaudium laevigatum
  • Leptospermum morrisonii

Project

We have assembled and annotated reference quality genomes for G. laevigatum and L. morrisonii, two Myrtaceae species endemic to Australia. These genome assemblies are useful resources for future research on the species biology, including studying traits related to nectar and foliage chemistry, and understanding the genetic diversity in their natural ranges. These genomes add to the collection of genomes in the large Myrtaceae family. Orthologous genes conserved between or unique to these species were identified, providing a resource for comparative genomics.

Funding

Funding was received from the New Zealand Ministry for Business Innovation and Employment (MBIE) Endeavour Smart Idea funding (C11X2102).

Tools Used

  1. Hifiasm Cheng, Haoyu, Gregory T. Concepcion, Xiaowen Feng, Haowen Zhang, and Heng Li. "Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm." Nature methods 18, no. 2 (2021): 170-175.

  2. BUSCO Simão, Felipe A., Robert M. Waterhouse, Panagiotis Ioannidis, Evgenia V. Kriventseva, and Evgeny M. Zdobnov. "BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs." Bioinformatics 31, no. 19 (2015): 3210-3212.

Seppey, Mathieu, Mosè Manni, and Evgeny M. Zdobnov. "BUSCO: assessing genome assembly and annotation completeness." In Gene prediction: methods and protocols, pp. 227-245. New York, NY: Springer New York, 2019.

  1. Samtools Li, Heng, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin, and 1000 Genome Project Data Processing Subgroup. "The sequence alignment/map format and SAMtools." bioinformatics 25, no. 16 (2009): 2078-2079.

Danecek, Petr, James K. Bonfield, Jennifer Liddle, John Marshall, Valeriu Ohan, Martin O. Pollard, Andrew Whitwham et al. "Twelve years of SAMtools and BCFtools." Gigascience 10, no. 2 (2021): giab008.

  1. assemblyQC Rashid, Usman, Chen Wu, Jason Shiller, Ken Smith, Ross Crowhurst, Marcus Davy, Ting-Hsuan Chen et al. "AssemblyQC: a Nextflow pipeline for reproducible reporting of assembly quality." Bioinformatics 40, no. 8 (2024): btae477.

  2. Ragtag Alonge, Michael, Ludivine Lebeigle, Melanie Kirsche, Katie Jenike, Shujun Ou, Sergey Aganezov, Xingang Wang, Zachary B. Lippman, Michael C. Schatz, and Sebastian Soyk. "Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing." Genome biology 23, no. 1 (2022): 258.

Liu, Kai, and Nan Xie. "Enhancing the Accuracy of Reference-Guided Genomic Assemblies: Implementing Ragtag Correction for Reference-Guided Scaffolds." (2024).

  1. genePal genepal: A Nextflow pipeline for genome and pan-genome annotation. Usman Rashid, Jason Shiller, Ross Crowhurst, Chen Wu, Ting-Hsuan Chen, Leonardo Salgado, Charles David, Sarah Bailey, Ignacio Carvajal, Anand Rampadarath, Ken Smith, Liam Le Lievre, Cecilia Deng, Susan Thomson zenodo. 2024. doi: 10.5281/zenodo.14195006.

  2. orthofinder Emms, David M., and Steven Kelly. "OrthoFinder: phylogenetic orthology inference for comparative genomics." Genome biology 20, no. 1 (2019): 238.

Emms, David M., and Steven Kelly. "OrthoFinder: solving fundamental biases in whole genome comparisons dramatically improves orthogroup inference accuracy." Genome biology 16, no. 1 (2015): 157.

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