diff --git a/linopy/solvers.py b/linopy/solvers.py
index 2783e7b8..597d49de 100644
--- a/linopy/solvers.py
+++ b/linopy/solvers.py
@@ -13,6 +13,7 @@
 import re
 import subprocess as sub
 import sys
+import threading
 import warnings
 from abc import ABC, abstractmethod
 from collections import namedtuple
@@ -56,6 +57,73 @@
 
 which = "where" if os.name == "nt" else "which"
 
+
+def _run_highs_with_keyboard_interrupt(h: Any) -> None:
+    """
+    Run `highspy.Highs.run()` while ensuring Ctrl-C cancels the solve.
+
+    HiGHS can run for a long time inside a C-extension call. Running it in a
+    worker thread allows the main thread to reliably receive KeyboardInterrupt
+    and signal HiGHS to stop via `cancelSolve()`.
+    """
+
+    handle_keyboard_interrupt = getattr(h, "HandleKeyboardInterrupt", None)
+    handle_user_interrupt = getattr(h, "HandleUserInterrupt", None)
+
+    old_handle_keyboard_interrupt = (
+        handle_keyboard_interrupt if not callable(handle_keyboard_interrupt) else None
+    )
+    old_handle_user_interrupt = (
+        handle_user_interrupt if not callable(handle_user_interrupt) else None
+    )
+
+    try:
+        if callable(handle_keyboard_interrupt):
+            handle_keyboard_interrupt(True)
+        elif handle_keyboard_interrupt is not None:
+            h.HandleKeyboardInterrupt = True
+
+        if callable(handle_user_interrupt):
+            handle_user_interrupt(True)
+        elif handle_user_interrupt is not None:
+            h.HandleUserInterrupt = True
+
+        finished = threading.Event()
+        run_error: BaseException | None = None
+
+        def _target() -> None:
+            nonlocal run_error
+            try:
+                h.run()
+            except BaseException as exc:  # pragma: no cover
+                run_error = exc
+            finally:
+                finished.set()
+
+        thread = threading.Thread(target=_target, name="linopy-highs-run", daemon=True)
+        thread.start()
+
+        try:
+            while not finished.wait(0.1):
+                pass
+        except KeyboardInterrupt:
+            cancel_solve = getattr(h, "cancelSolve", None)
+            if callable(cancel_solve):
+                with contextlib.suppress(Exception):
+                    cancel_solve()
+            while not finished.wait(0.1):
+                pass
+            raise
+
+        if run_error is not None:
+            raise run_error
+    finally:
+        if old_handle_keyboard_interrupt is not None:
+            h.HandleKeyboardInterrupt = old_handle_keyboard_interrupt
+        if old_handle_user_interrupt is not None:
+            h.HandleUserInterrupt = old_handle_user_interrupt
+
+
 # the first available solver will be the default solver
 with contextlib.suppress(ModuleNotFoundError):
     import gurobipy
@@ -912,7 +980,7 @@ def _solve(
         elif warmstart_fn:
             h.readBasis(path_to_string(warmstart_fn))
 
-        h.run()
+        _run_highs_with_keyboard_interrupt(h)
 
         condition = h.getModelStatus()
         termination_condition = CONDITION_MAP.get(
diff --git a/test/test_highs_keyboard_interrupt.py b/test/test_highs_keyboard_interrupt.py
new file mode 100644
index 00000000..71d5ce80
--- /dev/null
+++ b/test/test_highs_keyboard_interrupt.py
@@ -0,0 +1,47 @@
+from __future__ import annotations
+
+import _thread
+import threading
+import time
+
+import pytest
+
+from linopy.solvers import _run_highs_with_keyboard_interrupt
+
+
+class DummyHighs:
+    def __init__(self) -> None:
+        self.HandleKeyboardInterrupt = False
+        self.HandleUserInterrupt = False
+        self._cancel_event = threading.Event()
+        self.started = threading.Event()
+        self.finished = threading.Event()
+        self.cancel_calls = 0
+
+    def run(self) -> None:
+        self.started.set()
+        self._cancel_event.wait(timeout=5)
+        self.finished.set()
+
+    def cancelSolve(self) -> None:
+        self.cancel_calls += 1
+        self._cancel_event.set()
+
+
+def test_run_highs_cancels_on_keyboard_interrupt() -> None:
+    dummy = DummyHighs()
+
+    def interrupter() -> None:
+        assert dummy.started.wait(timeout=1)
+        time.sleep(0.05)
+        _thread.interrupt_main()
+
+    threading.Thread(target=interrupter, daemon=True).start()
+
+    with pytest.raises(KeyboardInterrupt):
+        _run_highs_with_keyboard_interrupt(dummy)
+
+    assert dummy.cancel_calls >= 1
+    assert dummy.finished.wait(timeout=1)
+    assert dummy.HandleKeyboardInterrupt is False
+    assert dummy.HandleUserInterrupt is False